Samantha Anders of Kettering died from injuries at the scene, according to OSHP.
Anders was in a 2016 Nissan Quest that was headed north on Clarksville Road when the driver, 39-year-old Anna Irwin of Kettering, reportedly failed to yield at a stop sign.
A 2016 Freightliner tractor-trailer combination was going through the intersection when the Nissan hit the truck’s left rear trailer tires, OSHP said.
CareFlight took Irwin to Miami Valley Hospital in Dayton with serious injuries.
Anders was a 2020 Ascension School graduate and incoming senior at Carroll High School, according to a social media post from Ascension Church in Kettering.
State Route 73 was closed in both directions between Corwin Road and Corwin Avenue Tuesday morning and has since reopened.
Warren County Sheriff’s Office, Wayne Twp. Fire Department & EMS and the Ohio Department of Transportation assisted on scene.
The crash is under investigation.