He said so far only one woman had been found alive and was being treated at a hospital. Police said rescuers will resume searching for missing passengers on Wednesday.
Police also said it was unclear what caused the crash, and officers were yet to record the lone survivor's statement.
Pakistani President Asif Ali Zardari offered condolences and asked rescuers to expedite efforts to find missing passengers.
Road accidents are common in Pakistan due to poor infrastructure and disregard for traffic laws and safety standards. In August, 36 people were killed and dozens of others were injured in two separate bus crashes.
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This version corrects the last name of the government spokesman to Faraq.