Khalil Haqqani is the uncle of Sirajuddin Haqqani, the acting interior minister who leads a powerful network within the Taliban.
Haqqani was the most high-profile casualty of a bombing in Afghanistan since the Taliban returned to power and the first Cabinet member to be killed since the takeover. There was no immediate claim of responsibility for the blast.
The government's chief spokesman, Zabihullah Mujahid, said in a post on X that Haqqani's death was a great loss and described him as a tireless holy warrior who spent his life defending Islam.
Haqqani's killing may be the biggest blow to the Taliban since their return to power given his stature and influence, according to Michael Kugelman, director of the Wilson Center’s South Asia Institute. It also comes at a time when the Taliban have staked their legitimacy on restoring peace after decades of war, he added.
“The killing of a top Haqqani leader inside one of its own ministries undercuts that core narrative,” he said.
Pakistan's Foreign Minister Ishaq Dar condemned the killing as a “terrorist attack.”
“Pakistan unequivocally condemns terrorism in all its forms and manifestations,” Dar said, adding his government was in touch with Kabul to get further details.
The Islamic State group’s affiliate, a major rival of the ruling Taliban, has carried out previous attacks across Afghanistan.
In early September, one of its suicide bombers in a southwestern Kabul neighborhood killed at least six people, wounding 13 others.
But suicide attacks have become increasingly rare since the Taliban seized power in August 2021 and U.S. and NATO forces withdrew. Such attacks have mostly targeted minority Shiite Muslims, especially in the capital.