The chamber voted 50-48, virtually along party lines with one Republican senator, Lisa Murkowski of Alaska, and one Democratic senator, Joe Manchin of West Virginia, breaking ranks.
The confirmation handed President Donald Trump a political victory that will likely change the tenor of the Supreme Court for years to come.
Related: As Kavanaugh joins Court, Trump, GOP try to seize election momentum
Kavanaugh’s nomination has been a contentious one amid charges of sexual misconduct and debates over whether Kavanaugh has the temperament to sit on the nation’s highest court.
Live updates
Update 8:45 p.m. EDT Oct. 7: Maine Republican Susan Collins was a key vote in the Senate's controversial confirmation of Judge Brett Kavanaugh to the U.S. Supreme Court.
Collins spent Sunday making the rounds on the weekend news shows defending her vote amid harsh criticism and threats against her anticipated re-election bid in 2020.
"This was a tough one," she told John Dickerson on "Face the Nation."
“I have to do what I think is right. Over the years, the people of Maine have trusted me to exercise my best judgment. That’s what I did in the case," Collins said.
“Whatever the voters that decide, but I’m going to do what I think is right. That’s what I owe my constituents," she said.
On @FaceTheNation, Sen. Susan Collins defends Brett Kavanaugh's temperament during his sexual assault allegation hearing: "His anger and his anguish, I think, are understandable... He was reacting as a human being, as a father of two young girls" https://t.co/cT4uJZGiIs pic.twitter.com/6qGCQAoXat
— CBS News (@CBSNews) October 7, 2018
Collins also defended Kavanaugh’s temperament during his Senate hearing over the sexual assault allegation by Christine Blasey Ford.
"His anger and his anguish, I think, are understandable ... He was reacting as a human being, as a father of two young girls," she said.
But Democratic colleagues, like Sen. Mazie Hirono (D-HI), criticized Collins’ reasoning in voting to confirm Kavanaugh.
Hirono said on “State of the Union” that it’s hard to understand Collins’ reasoning in light of Ford’s credible testimony.
Collins said she didn’t believe that Kavanaugh assaulted Ford.
“She said that Dr. Ford thinks she was assaulted, which is even more insulting then saying she gave a very credible account.”
“To say that she (Collins) thinks that Dr. Ford thinks she was assaulted, what is that?” Hirono said.
"To say that she thinks that Dr. Ford thinks that she was assaulted, what is that?"
— The Hill (@thehill) October 8, 2018
Sen. Mazie Hirono slams Sen. Susan Collins for her reasoning for voting to confirm Brett Kavanaugh to the U.S. Supreme Court. https://t.co/0HdM4jT4qB pic.twitter.com/nVj5ktOWH7
Update 10:50 a.m. EDT Oct. 7: Julie Swetnick, the third person accusing Kavanaugh of sexual misconduct, released a statement through her attorney Michael Avenatti.
In her statement, Swetnick criticized some members of the media and politicians who were critical of her coming forward during the nomination process.
“They claim my allegations were ‘not helpful to the process.’ This is outrageous and shows a complete lack of empathy for survivors,” she said. “I had every right to come forward and I literally placed my life in jeopardy to do so.”
Swetnick also criticized Trump, Sen. Susan Collins, Sen. Ted Cruz and others for affecting the FBI investigation into Kavanaugh.
“They purposely prevented any inquiry into my claims and those of other sexual assault victims in the interest of politics,” she said. “They then had the audacity to claim our claims were not credible even though they never allowed any investigation to determine their credibility...
“Senator Susan Collins’ actions on Friday were especially shameful and an attack on all sexual assault victims. She showed herself to be someone that cares more about politics than women and victims.”
Read Swetnick's full statement below:
Below please find a statement from my client Julie Swetnick regarding the Kavanaugh nomination. I urge you to read it. pic.twitter.com/kBHL7cm8Pi
— Michael Avenatti (@MichaelAvenatti) October 7, 2018
Update 7:09 a.m. EDT Oct. 7: President Donald Trump took to Twitter on Saturday night to slam Democrats after Brett Kavanaugh's confirmation to the Supreme Court.
"You don't hand matches to an arsonist, and you don't give power to an angry left-wing mob," Trump tweeted. "Democrats have become too EXTREME and TOO DANGEROUS to govern. Republicans believe in the rule of law - not the rule of the mob. VOTE REPUBLICAN!"
You don’t hand matches to an arsonist, and you don’t give power to an angry left-wing mob. Democrats have become too EXTREME and TOO DANGEROUS to govern. Republicans believe in the rule of law - not the rule of the mob. VOTE REPUBLICAN!
— Donald J. Trump (@realDonaldTrump) October 7, 2018
The comments came after Trump spoke at a rally in Topeka, Kansas, calling Democrats a “radical, angry mob” and singing Kavanaugh’s praises.
“I stand before you today on the heels of a tremendous victory for our nation, our people and our beloved Constitution,” Trump said at the rally.
Thank you Kansas - I love you! https://t.co/ymCFNr9WQY
— Donald J. Trump (@realDonaldTrump) October 7, 2018
Beautiful evening in Topeka, Kansas. VOTE, VOTE, VOTE! #MAGA pic.twitter.com/bomRqsaYfm
— Donald J. Trump (@realDonaldTrump) October 7, 2018
Update at 10 p.m. EDT Oct. 6: President Donald Trump told reporters from Air Force One that he is a "hundred percent" sure that the woman accusing Brett Kavanaugh of sexually assaulting her when they were in high school named the wrong person.
I asked @realDonaldTrump about his previous comments when he said there “shouldn’t even be a little doubt.” “Are you 100% certain that Ford named the wrong person?” POTUS: I’m a hundred percent. I’m a hundred percent. I have no doubt.”
— Katherine Faulders (@KFaulders) October 6, 2018
Trump also told reporters on Air Force One that one of the reasons he chose Kavanaugh “is because there’s nobody with a squeaky-clean past” like him.
Update at 7 p.m. EDT Oct. 6: Brett Kavanaugh was sworn in as a Supreme Court justice Saturday night after the U.S. Senate narrowly confirmed him.
Credit: Fred Schilling
Credit: Fred Schilling
Kavanaugh was quickly sworn in at the court building, across the street from the Capitol, even as protesters chanted outside.
Update at 4:50 p.m. EDT Oct. 6: Kavanaugh will be sworn in later Saturday by Chief Justice John Roberts and retired Associate Justice Anthony M. Kennedy.
Update at 4:15 p.m. EDT Oct. 6: Trump tweets:
I applaud and congratulate the U.S. Senate for confirming our GREAT NOMINEE, Judge Brett Kavanaugh, to the United States Supreme Court. Later today, I will sign his Commission of Appointment, and he will be officially sworn in. Very exciting!
— Donald J. Trump (@realDonaldTrump) October 6, 2018
Update at 4 p.m. EDT Oct. 6: Kavanaugh's nomination passes on a 50-48 vote.
Update at 3:49 p.m. EDT Oct. 6: Manchin is the first Democrat to vote "yes." Murkowski withdraws her vote, mentioning Sen. Steve Daines who is attending his daughter's wedding.
Update at 3:46 p.m. EDT Oct. 6: Protesters are screaming again.
Update at 3:45 p.m. EDT Oct. 6: The clerk is calling the roll for votes.
Update 3:44 p.m. EDT Oct. 6: Vice President Mike Pence is presiding over the vote. A protester is being taken from the chamber. More protesters are screaming.
Update 3:34 p.m. EDT Oct. 6: Sen. Sen. Mitch McConnell is speaking now. "The courts guard our rights, and the Senate guards our courts."
Update 3:27 p.m. EDT Oct. 6: Sen. Minority Leader Chuck Schumer is speaking now. He is deriding the Republicans for pushing Kavanaugh's nomination through the confirmation process. He calls for Americans to make their wishes known at the ballot box. "If you believe the Supreme Court must uphold women's rights, vote."
Update 3:15 p.m. EDT Oct. 6: As senators begin to gather for the vote, Senate Majority Leader Mitch McConnell, R-Kentucky, told Fox News that the confirmation process had been "nasty," but "nothing has been irreparably damaged" when it came to Brett Kavanaugh's confirmation.
McConnell said the actions of the Democrats, “played right into our hands, in retrospect.”
Update 2:50 p.m. EDT Oct. 6: Jamie Dupree sets the scene in Washington:
Big crowd just rushed up the Capitol steps pic.twitter.com/WcVyoDqIaT
— Jamie Dupree (@jamiedupree) October 6, 2018
Update 2:38 p.m. EDT Oct. 6: Here's what Sen. Bob Corker, R-Tennessee, says about his vote:
.@SenBobCorker: “I’m very confident in my vote. I’m looking forward to it. I talked to Judge Kavanaugh this morning and thanked him for his willingness to serve the country.” pic.twitter.com/41V12Inf9X
— Fox News (@FoxNews) October 6, 2018
Update 2:25 p.m. EDT Oct. 6: The New York Times is reporting that Rep. Jerrold Nadler, D-New York, says his party will open an investigation into allegations of sexual assault and perjury against Brett Kavanaugh if Democrats win control of the House in November.
“It is not something we are eager to do,” Nadler told the Times on Friday.
Nadler said that because the Senate “failed to do its proper constitutionally mandated job of advise and consent, we are going to have to do something to provide a check and balance, to protect the rule of law and to protect the legitimacy of one of our most important institutions.”
Update 2:10 p.m. EDT Oct. 6: How will the vote be taken? Like this:
On the Kavanaugh vote...a Senate clerk will verbally call the roll of all 100 senators alphabetically, starting with Sen. Lamar Alexander (R-TN) and culminating with Sen. Todd Young (R-IN). Senators will rise from their desks and vote yea or nay.
— Chad Pergram (@ChadPergram) October 6, 2018
Update 1:50 p.m. EDT Oct. 6: First lady Melania Trump offered her support to Brett Kavanaugh from Africa where she is on a trip.
“I think he's highly qualified for the Supreme Court,” the first lady told reporters traveling with her in Egypt on the final leg of her four-country tour of Africa.
Update 1:30 p.m. EDT Oct. 6: The vote to confirm Brett Kavanaugh to the Supreme Court is now expected to take place at 3:30 p.m. EDT.
The timing of the Kavanaugh vote is being moved up - we are being told it could start as between 3:30-3:45 pm ET
— Jamie Dupree (@jamiedupree) October 6, 2018
Update 1:21 p.m EDT Oct. 6: People continue to protest in Washington.
WATCH: Protesters gather at Capitol ahead of Kavanaugh vote https://t.co/CRW4hXhFPR
— NBC News (@NBCNews) October 6, 2018
Update 12:50 p.m. EDT Oct. 6: Sen. Lisa Murkowski, R-Alaska, is expected to be voting "present" instead of "no" during the vote on Brett Kavanaugh's Supreme Court confirmation so that Sen. Steve Daines, R-Montana, can attend his daughter's wedding, according to Fox News.
Murkowski broke with Republicans on Friday to vote “no” on ending debate on Kavanaugh’s confirmation.
Daines had said he would attend his daughter’s wedding then fly back to Washington Saturday night to vote in favor of Kavanaugh if his vote was needed.
If Murkowski votes “present” and not “no” then Daines’ vote would not be needed to confirm Kavanaugh to the court.
Update 12:21 p.m. EDT Oct. 6: Capitol Police said they arrested 101 people Friday as they protested Brett Kavanaugh's confirmation to the Supreme Court. Seventy-eight were arrested for unlawfully demonstrating in Senate office buildings and six were arrested on the Senate Gallery for protesting during Maine Sen. Susan Collins' speech on the floor.
Sixteen were also arrested for blocking the street in front of the Supreme Court, and one was arrested for marijuana use.
Update 11:59 a.m. EDT Oct. 6:
President Donald Trump has tweeted his support for the upcoming confirmation vote.
Women for Kavanaugh, and many others who support this very good man, are gathering all over Capital Hill in preparation for a 3-5 P.M. VOTE. It is a beautiful thing to see - and they are not paid professional protesters who are handed expensive signs. Big day for America!
— Donald J. Trump (@realDonaldTrump) October 6, 2018
The Associated Press contributed to this report.
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