In the third quarter Cooper Stewart hit Carl Blanton Jr. on a 50-yard touchdown pass and Huguely rumbled for a 47-yard score to put Trotwood up 21-0.
St. Marys trimmed the deficit to 21-7 on a TD throw with 5:02 to play, but Trotwood answered with a third rushing score from Huguely and a pair of scoop-and-scores to blow the game open.
Huguely finished with 130 yards on the ground and three TDs and 64 yards receiving on offense along with 10 tackles and a fumble recovery for a TD on defense.
Trotwood (9-3) advances to the regional finals next Friday night against Badin (9-3), which defeated Alter 38-21 on Friday.
OTHER GAMES
Division VI, Region 23
Anna 54, Fairview 20: Anna trailed 14-0 early but recovered by halftime and ran away in the second half, winning a second round playoff game for the first time in school history.
Riley Huelskamp led the way, rushing for over 300 yards and scoring six touchdowns. Anna (11-1) will look to take home the school’s first regional title when they square off with Archbold next Friday.
Division VI, Region 24
Covington 36, Chillicothe Southeastern 20: Trentin Alexander had two rushing touchdowns in the second half to help Covington eliminate unbeaten Southeastern.
Covington (10-2) will face Mechanicsburg next Friday. It marks the first regional final appearance for Covington since 2012.
Mechanicsburg 48, Grandview Heights 7: Chayse Propst scored four touchdowns for Mechanicsburg (10-2), finishing with 16 carries for 193 yards. Gabe Chandler added a pair of TD runs and Kix Thiel recovered a fumble for a score.